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![]() ![]() In the Windows Update window, check for and install all critical Windows updates. If your Start menu isn’t working, use Windows Key + I to open Settings. Select the Start menu and select the Settings icon. ![]() A good quick-fix for this is just to make sure you have all of the latest critical Windows updates. If the problem is still happening, it’s very possible your version of Windows 10 is out of date and buggy. After this, select the Windows 10 Start menu and see if the issues you were having are now resolved. Give the computer a few moments to automatically restart the Windows Explorer process. You will see your desktop blink a few times, and the taskbar may actually disappear. Right-click Windows Explorer and select End task. Then scroll down to Windows Explorer under the Windows Processes section. Select the Name field to sort apps and processes by name. To restart Windows Explorer, press Ctrl + Shift + Esc to open the Task Manager. This is also the software that serves the Start menu, so restarting it can resolve a lot of Start menu issues. Restart Windows ExplorerĪnother issue that happens when you use a Windows 10 computer for a long time is that Windows Explorer can get glitchy. Once you log back into your, test the Start menu to see if the lag is gone. It’s good to do this from time to time to keep your system running at peak performance. By restarting the system, everything will get closed out, memory and cache flushed, etc. We mention a full Restart because, for many of us, we don’t restart our computers very often. The Windows 10 Shut down menu will appear and you can choose to either Sign out or do a full Restart. To log out, click on your Desktop (not on an app) and press the keyboard shortcut ALT+F4. So a great quick fix for Windows 10 Start menu issues is simply logging out and back in. When you log out and then back into your account, many of these things are cleared and refreshed. If you stay logged in for long periods of time (as is usually the case with a computer that only has one user), this cache can eventually get very large or corrupted. Sign Out of Your Microsoft AccountĪs each user signs in to their Microsoft account on a Windows 10 computer, many of the apps and other things listed on the Start menu get cached. We’ll work down this list from the easiest quick fixes to the more complex and involved ones. Now to get to the fixes and tweaks that will resolve this issue. How to Fix Windows 10 Start Menu Not Opening Windows Explorer on your system is out of date or includes corrupted files.The Start menu under your specific Windows account is crashing or missing.A known glitch in Windows 10 that causes the Start menu to freeze.Cortana temporary files are corrupt or out of date.Temporary data files that the Start menu uses are corrupt or out of date.Why does this even happen? There are numerous causes, including: ![]() It’s the second behavior that’s the most common, and it’s especially annoying because past versions of Windows always had instantaneous Start menus. It either won’t open at all, or it takes more than 5 seconds to finally open. There are two main behaviors that can start happening with the Windows 10 Start menu. Windows 10 Start Menu Not Opening: Why It Happens Use the following tips to get the Start menu working quickly for you again. However, you don’t have to tolerate it any longer. Most people just tolerate this annoyance, since eventually, the Start menu will begin working again. ![]() ![]() ![]() In Accessibility Settings, disabled "Allow animated images and emoji" and Slack is idling at 0-1% and Slack Helper at 0-1%. Type /giphy followed by the word or phrase which you want to send. After integrating Giphy, it is a piece of cake to send GIFs. Click Shuffleto view more options, then select Shareto post your GIF. Type a word or phrase in the text field, then click Search. Search for and select Find and share a GIFfrom the menu. In Advanced Settings, just turned on "Disable Emoji Spritesheet" and slack is idling at 7-9%, Slack Helper at 27-30%. Sending GIFs on Slack is not a tough job. Send GIFs in Slack From a conversation, click the plus iconnext to the message field. Reacted to a message with 10 animated gifs, slack is idling at 9-12%. Ran /collapse and both are back down to 0-1%. A Slack Helper task started to run at 12%. Type '/giphy' (without quotes) into the message bar, followed by a word or phrase that you want. I removed that comment and then posted using /giphy, now it's idling at 2-3%. How to use GIPHY in Slack to send GIFs Using the desktop app, the browser app, or the mobile app: 1. I just added 1 animated gif reaction to a comment and it's idling at 4-6%. In my test locally, a chat window with no animated things is idling at 0-1.5% CPU. Reactions to comments with animated gifs are the worst, because /collapse wont hide them. ![]() Lots of them and you're going to idle even higher.ĭon't leave slack open on a channel where people frequently use /giphy or post lots of animated emojis (#random, etc). ![]() Animated things are why Slack will idle at 5%+. Other tips I've ritualized, use /collapse very often when on slack, and avoid message reactions with animated gifs. I have suggested to them that they should have a setting to only play gifs when they're hovered-over, but still waiting on that to be implemented. this also removes some of the fun from Slack. The best perf improvement for slack is to disable animated images in the Accessibility Settings. ![]() ![]() The tools described on this page are provided using Search and sequence analysis tools services from EMBL-EBI in 2022 These specialist programs allow searches of databases using sequence fragments as the query. This can be useful when you want to match all of a short query sequence to part of a larger database sequence. GLSEARCH performs an optimal sequence search using alignments that are global in the query but local in the database sequence. GGSEARCH performs optimal global-global alignment searches using the Needleman-Wunsch algorithm. PSI-Search2 combines the sensitivity of the Smith-Waterman search algorithm (SSEARCH) with the PSI-BLAST profile construction strategy to find distantly related protein sequences. PSI-Search combines the sensitivity of the Smith-Waterman search algorithm (SSEARCH) with the PSI-BLAST profile construction strategy to find distantly related protein sequences. ![]() Optimal searches guarantee you find the best alignment score for your given parameters. SSEARCH is an optimal (as opposed to heuristics-based) local alignment search tool using the Smith-Waterman algorithm. Protein Nucleotide Genomes Whole Genome Shotgun ![]() PHI-BLAST functionality is also available to restrict results using patterns.įASTA is another commonly used sequence similarity search tool which uses heuristics for fast local alignment searching. PSI-BLAST allows users to construct and perform a BLAST search with a custom, position-specific, scoring matrix which can help find distant evolutionary relationships. It uses heuristics to perform fast local alignment searches. NCBI BLAST is the most commonly used sequence similarity search tool. The tools can be launched with different form pre-sets using the links - these can be changed on the tool page as well. By statistically assessing how well database and query sequences match one can infer homology and transfer information to the query sequence. The Spectral Similarity Score (SSS) is an extension to the conventional similarity methods and results indicate that it holds a strong potential for analysis of various biological sequences and structural variations in proteins.Sequence Similarity Searching is a method of searching sequence databases by using alignment to a query sequence. The method captures subsequences that do not align by traditional character based alignment tools but give rise to similar secondary and tertiary structures. Comparison of 3D structures of the subsequences confirmed the claim of similarity in structure.Īn algorithm is developed which is inspired by successful application of spectral similarity applied to music sequences. Similarly many subsequences with low character identity were picked between xyna-theau and xyna-clotm F/10 xylanases. We compared their known 3D structures to establish that the algorithm is able to pick subsequences that are not considered similar by character based matching algorithms but share structural similarities. Detailed comparison established close similarities between subsequences that do not have any significant character identity. PKCd and PKCe kinases share close biological properties and structural similarities but do not give high scores with character based alignments. This approach finds a similarity score between sequences based on any given attribute, like hydrophobicity of amino acids, on the basis of spectral information after partial conversion to the frequency domain.ĭistance matrices of various branches of the human kinome, that is the full complement of human kinases, were developed that matched the phylogenetic tree of the human kinome establishing the efficacy of the global alignment of the algorithm. We present a method based on spectral similarity to compare subsequences of amino acids that behave similarly but are not aligned well by considering amino acids as mere characters. However, character based similarity cannot provide insight into the structural aspects of a protein. Several algorithms have been developed which determine alignment and similarity of primary protein sequences. ![]() The chemical property and biological function of a protein is a direct consequence of its primary structure. ![]() ![]() I already had been using projects in Toggl for this, so I just copied them into Headspace. I started adding entries for time tracking every major modality of work that I do daily, even if it didn't require a special window layout. Removing distraction, staying focused, and tracking how much time I spend moving the needle. 102.Īs I already was copying Grey's use of toggl to track my whole work day, I realized I could build a tool of spatial intentionality. I had been really interested in the idea or having different spaces for productivity, since I had seen Spaceship You and heard CGP Grey's additional commentary on the topic in Cortex Ep. Headspace had become a tool that cleared the space for me to focus on my intent, and automatically removed obstacles. I realized that choosing a space was a statement of intentionality. I pressed one key, chose my task, and started to work. Within a couple minutes or hacking, I had a button than when pressed could rearrange my computer into one of two "scenes," which immediately set up my workspace and started the correct toggl timer. I could automate my time tracking as well! I wrote the first curl-based version of my a script and threw a toggl.start() call in the setup function. I realized that since I'm writing a function for a specific task, then I know the time tracking data for that task. I started with a hs.chooser, and just had it wired to functions that moved around windows and set up the windows in my workspace the way I wanted it. In early May, I started to write a simple "layout chooser". I have the To-do with a checklist for the ritual itself on the right, and I work in the pane to the left as I work through the checklist. This is how I like to conduct my daily review. I then follow the checklist in the right window to do the work in the left window.I open a second Things window ( CMD+OPT+N).I launch Things and Drafts using a hotkeys.I start a timer using Toggl.app, I choose "Planning" as the project and type in "Review" as the description. ![]() I close all distracting apps by running "quitall" in Alfred.To have an idea of the complexity of one of these tasks: Every work weekday at 4:30p in order to perform my Daily Review… 1 Build your own version or clone mine! How Headspace Came to BeĪfter writing the "split window" function, I realized there were window layouts I preferred for specific tasks… starting with my daily review in Things 3, but also my daily standup. I am sure that you could create something very similar using a variety of automation tools. I've been using Headspace daily for about a month. tracking presets per space… or a custom input at any time. ![]() Block distracting a shortcuts to protect focus.Launch relevant applications and quit distracting applications based on tags.Define workspaces for your important work:.Fully configurable for you and your work-style.If you want to share this video with someone, it's on youtube. Headspace has been the title of this series, and it's what I call the last automation in this series. I'm pretty sure that I've been working on it alongside the name-sake tool for a straight month. Workers Are Using ‘Mouse Movers’ So They Can Use the Bathroom in Peace I used this about a decade ago, not sure it's still maintained.Of course if you just want mac based keybinds to be done for you then use my kinto app. Switching from macOS to Pop _OS Https:///autokey/autokey My advice is to skip the last one unless you need something truly complicated and a config syntax that is just insane regardless of your level of complexity imo.I have the contents of ~/.config/sxhkd/sxhkdrc as. I want to implement macros whereby when I press alt + j,i,k,l it simulates left,up,down,right arrow keys respectfully. ![]() I've seen some suggest sxhkd combined with xdotool, which is what I'm trying here.
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While emailing the company is free, you have to pay for a phone support plan if you want to get technical help. You'll find tutorials and a FAQs page on the website. This software also makes it easy to post your favorite images directly to Facebook or send your photos to loved ones using email from within the program. PhotoDirector works with the most common image file types including PSD, JPG, TIFF and RAW files. Instead of simply clicking on the cloning brush icon in the toolbar, you'll need to click on the 'People Beautifier' tab in the 'Edit' section to access this feature. Instead of displaying toolbar icons, the program is split into category tabs, which contain various editing tools. The interface is built differently than many other photo editing programs. Unfortunately, there were no vector graphics tools. We also found an easy HDR feature and lens distortion correction tools. The object removal tool was especially impressive, removing unwanted elements and replacing the space believably. There is a wide range of editing tools and we found that they work super well when making changes. You can arrange your photos using a star rating system, color labels, keyword tags and even by tagging specific people's faces. Productīest Overall CyberLink PhotoDirector Ultra 10 PhotoDirector 365 MonthlyĮxperienced users will also find that it offers the tools needed to edit and organize their work. One of the biggest differences between the two programs is Affinity's lower-cost. 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AUX Magazine -This site creates a community with location-based listings for conferences, jobs, workshops, informal meetups, and classes.ģ. But still, I don't see any difference in the resulting artboard.1. Of note, some were created using the iPhone 8 template whereas others I tried using 'from selection' to save time. The weird thing is when using the 'Preview' feature, some artboards show full-width and scroll (as I would expect), while other artboards show the entire artboard, scaled down to fit so it's tiny with huge black bars on the sides.Ĭhecking the inspector on both the artboards as well as the images, I don't see any difference between those that scroll vs. create artboards for the pages, drag the images onto the artboards, then use the 'Fit' button to size the artboard to the content (which changes the height since the widths already match.) ![]() I have a bunch of PNG screenshots (iPhone 8 resolution so 750px wide, or and I want to build a quick click-through prototype in Sketch. Still trying to wrap my head around Sketch and how it works. ![]() |